Don’t misunderstand me. Prezi is a very powerful, very awesome tool! If you haven’t tried it out, well you should. That being said, it is possible to do some of what Prezi does in PowerPoint. I give you this very simple example:
In the video above you will see a PowerPoint presentation consisting of 10 slides. The movement is created with very simple transitions between the slides called PUSH transitions. You can download the PowerPoint here.
You can use this effect to create some very powerful effects and animations in your presentation, though beware – people come to see a person speak, not to see how mad their PowerPoint skills are!
Hope this helps!